老年住院慢性阻塞性肺疾病患者合并抑郁的临床相关分析

Clinical analysis of depression in hospitalized elderly patients with chronic obstructive pulmonary disease

中文关键词: 慢性阻塞性肺疾病  抑郁症  慢性阻塞性肺疾病评估测试  医院焦虑抑郁情绪测量表

英文关键词: chronic obstructive pulmonary disease  depression  COPD assessment test  hospital anxiety and depression scale

中文摘要:

      目的 分析老年慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者抑郁状况及与临床情况的相关性.方法 选择2014年1月-2015年2月354例老年住院COPD患者,通过医院焦虑抑郁情绪测量表(hospitalanxiety and depression scale,HAD)进行抑郁状态评估,收集临床资料和肺功能数据并进行相关分析.结果 354例老年住院COPD患者中,抑郁组(HAD≥11分)306例,非抑郁组(HAD＜11分)48例.抑郁组和非抑郁组患者年龄、第1秒用力呼气容积(forced expiratory volume in one second,FEV1)、慢性阻塞性肺疾病评估测试(COPD assessment test,CAT)差差无统计学意义(P＞0.05);抑郁组患者体质指数(body mass index,BMI)、急性加重次数、FEV 1％pred高于非抑郁组(均P＜0.05).相关分析提示CAT和抑郁评分呈正相关(r=0.44,P=-0.011);年龄和抑郁评分无相关性(r=0.025,P=0.861);BMI、FEV1％pred和抑郁呈负相关(r=-0.467,P=0.007;r=-0.28,P=0.02).结论 老年住院COPD患者抑郁发病率高,其发生与CAT呈正相关,与BMI、FEV1％pred呈负相关.

英文摘要:

      Objective To analyze the depression in hospitalized elderly patients with chronic obstructive pulmonary disease (COPD) and clinical correlation.Methods Using hospital anxiety and depression scale (HAD) to evaluate depression from 354 hospitalized elderly patients with COPD,collected clinical cases and lung function data from January 2014 to February 2015 and related analysis.Results A total 306 people accorded the provisions of this study from 354 hospitalized elderly patients with COPD.In the depressed group and non-depressed group,age,forced expiratory volume in one second (FEV1),COPD assessment test (CAT) were not statistically significant (P＞0.05).The depressed group's body mass index (BMI),exacerbations,FEV1％ pred are higher than non-depressed group's (all P ＞ 0.05).Correlation analysis showed that CAT and depression scores were positively correlated (r=0.44,P=0.011).Age and depression scores were no significant correlation (r=0.025,P=0.861).BMI and depression scores were negatively correlated (r=-0.467,P=0.007).FEV1％ pred and depression scores were negatively correlated (r=-0.28,P=0.02).Conclusion Hospitalized elderly patients with COPD have a high incidence of depression.Depression was positively correlated with CAT,whereas negatively correlated with BMI and FEV1％ pred.