降钙素原、C-反应蛋白和红细胞沉降率联合检测在诊断老年细菌性肺炎中的临床意义

Clinical Significance of Combined Detection of PCT, CRP and ESR in the Diagnosis of Bacterial Pneumonia in Elderly Patients

中文关键词: 老年  细菌性肺炎  降钙素原  C-反应蛋白  红细胞沉降率

英文关键词: elderly  bacterial pneumonia  procalcitonin (PCT)  C-reactive protein (CRP)  erythrocyte sedimentation (ESR)

中文摘要:

      目的 探讨联合检测降钙素原(PCT)、C-反应蛋白(CRP)以及红细胞沉降率(ESR)对诊断老年细菌性肺炎的意义.方法 收集老年细菌性肺炎患者86例作为观察组,以同期老年非感染性疾病住院患者88例作为对照组.分别记录各组患者入院时外周血PCT、CRP和ESR检测值,并对结果进行统计学分析与比较.结果 观察组外周血中PCT、CRP和ESR水平均较对照组明显升高(均P＜0.01).通过与肺CT诊断结果的比较,PCT、CRP和ESR对肺炎的诊断敏感性及特异性均较高,且联合三者分析,对老年肺炎诊断的敏感性升高.结论 血清PCT、CRP和ESR均为诊断老年肺炎的敏感指标,但联合检测可提高诊断特异性,对准确诊断具有临床意义.

英文摘要:

      Objective To explore the clinical significance of combined detection of procalcitonin (PCT),C-reactive protein (CRP) and erythrocyte sedimentation (ESR) in diagnosing bacterial pneumonia of the elderly.Methods 86 senile patients with bacterial pneumonia were collected to constitute observation group while 88 senile patients with non-bacterial infection were selected to constitute control group;the levels of serum PCT,CRP and ESR of the elderly in the 2 groups at admission were recorded respectively and statistical analysis and comparison were made.Results The levels of serum PCT,CRP and ESR of the elderly in observation group were significant higher than those of the elderly in control group (P＜0.05);the comparison with CT scanning indicated that serum PCT,CRP and ESR were of high sensitivity and specificity to pneumonia and the combined detection of the 3 made the sensitivity to pneumonia increase even higher.Conclusions Serum PCT,CRP and ESR are sensitive indexes in diagnozing bacterial pneumonia in elderly patients,and the combined detection may raise the specificity,which is of clinical significance for accurate diagnosis.