亚肺叶切除术与肺叶切除术治疗老年磨玻璃结节的疗效比较

Comparison of Curative Effect between Sublobar Resection and Lobectomy on the Elderly with Ground-glass Opacities

中文关键词: 老年患者  肺癌  磨玻璃结节  亚肺叶切除

英文关键词: elderly patient  lung cancer  ground-glass opacities (GGOs)  sublobar resection

中文摘要:

      目的 总结分析亚肺叶切除术(肺段切除术、肺楔形切除术)与肺叶切除术对70岁以上老年磨玻璃结节的预后疗效.方法 回顾2010年1月-2013年12月期间进行手术切除的243例70岁以上老年磨玻璃型肺癌患者.其中肺段切除术32例,肺楔形切除术112例,肺叶切除术99例,分析3组患者的远期预后.结果 全组患者3年总生存率为84.3％;3组患者3年无病生存率(DFS)相似(肺段切除组96.3％、楔形切除组98.9％、肺叶切除组97.3％,P=0.42),3组患者3年总生存率(OS)相近(楔形切除组87.3％、肺段切除组87.9％、肺叶切除组85.3％,P=0.63).结论 70岁以上老年磨玻璃结节型肺癌患者,亚肺叶切除术(肺段切除术、肺楔形切除术)能取得与肺叶切除术相似的远期预后,亚肺叶切除术可作为70岁以上老年磨玻璃结节可选择地根治性手术.

英文摘要:

      Objective To summarize and analyze the sublobar resection (segmentectomy of lung and pulmonary wedge resection) or lobectomy in the elderly at 70 and over 70 with lung ground-glass opacities (GGOs) and to evaluate the effects on the prognosis.Methods A retrospective analysis was made to the clinical data of 243 elderly patients at 70 and over 70 undergoing surgical resections for lung cancer with GGOs;according to surgical strategy,32 cases were classified into segmentectomy group,99 cases into lobectomy group and 112 cases into wedge resection group;the long-term prognosis of the patients were analyzed.Results The 3-year overall survival (OS) was 84.3％;the 3-year disease free survival (DFS)in each of the 3 groups was similar (96.3 ％ in segmentectomy group,98.9 ％ in wedge resection group and 97.3 ％ in lobectomy group,P=0.42),as well as the 3-year OS in each of the 3 groups (87.3％ in in wedge resection group,87.9％ in segmentectomy group and 85.3 ％ in lobectomy group,P=0.63).Conclusions Sengmentectomy and wedge resection for lung cancer with GGOs can lead to similar long-term prognosis in elderly patients over 70 years old to lobectomy,they can be taken as the radical surgical treatment.