运动训练对老年糖尿病周围神经病变患者平衡功能影响的Meta分析

Effect of Exercise Training on Balance Function of the Elderly with Diabetic Peripheral Neuropathy: A Meta Analysis

中文关键词: 糖尿病  周围神经病变  运动训练  平衡功能  Meta分析

英文关键词: diabetes  peripheral neuropathy  exercise training  balance function  Meta analysis

中文摘要:

      目的 评价运动训练对老年糖尿病周围神经病变(DPN)患者平衡功能的影响.方法 计算机检索Cochrane Library、JBI、MEDLINE、EMbase、PubMed、Web of Science、中国生物医学文献数据库(CBM)、中国知网(CNKI)及万方数据库中(自建库至2017年2月5日)关于运动训练对老年DPN患者平衡功能影响的随机对照试验(randomized controlled trial,RCT),由2名研究员按纳入和排除标准筛选文献、提取资料并评价质量,然后采用RevMan 5.3软件进行Meta分析.结果 共纳入6个RCT,373例老年DPN患者.Meta分析结果显示,运动训练可延长老年DPN患者的睁眼/闭眼单足站立时间[WMD=3.8,95％CI (2.38～5.22),P＜0.00001;WMD=I.66,95％CI (0.86～2.46),P＜0.0001],增加Berg平衡功能量表得分[WMD=1.34,95％CI (0.93 ～ 1.75),P＜0.00001],缩短计时起立-步行测试时间[WMD=-1.37、95％CI (-1.69～-1.05),P＜0.00001].结论 运动训练可显著改善老年DPN患者的静态和动态平衡功能,临床上应注重对老年DPN患者进行运动训练,从而改善其平衡功能,降低跌倒风险.

英文摘要:

      Objective To evaluate the effect of exercise training on the balance function of the elderly with diabetic peripheral neuropathy (DPN).Methods Papers with randomized controlled trials (RCT) involving the effect of exercise training on the balance function of the elderly with DPN,published since the setup of the databases to Feb.5 th.,2015,were searched in Cochrane Library,JBI,MEDLINE,EMbase,PubMed,Web of Science,CBM,CNKI and WanFang Data;according to the inclusion and exclusion criteria,the papers were screened by 2 researchers;data were extracted and the methodological quality of the included was assessed.Result In total,6 RCTs involving 373 elderly with DPN were included;Meta analysis indicated that after exercise training,the elderly with DPN had a longer time of one leg stance with eyes opening (WMD =3.8,95％CI 2.38-5.22,P＜ 0.00001),as well as a longer time of one leg stance with eyes closing (WMD=1.66,95 ％ CI 0.86-2.46,P ＜ 0.0001);and the exercise training increased the scores of Berg balance scale (WMD =1.34,95 ％ CI 0.93-1.75,P＜0.00001) and shortened the time of up and go tests (WMD=-1.37,95％CI-1.69--1.05,P＜0.00001).Conclusion Exercise training can obviously improve the static and dynamic balance function of the elderly with DPN;more attention should be paid to exercise training in clinic so as to improve the balance function of the elderly and decrease the risk of falling.