上海市静安寺社区老年人群抑郁与冠心病的相关性队列研究

Cross-sectional study on the Correlation between Depression and Coronary Heart Disease in the Elderly Population in Jing'an Temple Community, Shanghai

中文关键词: 老年人群  冠心病  抑郁  流行病学研究用抑郁自评量表

英文关键词: elderly population  coronary heart disease (CHD)  depression  center for epidemiological studies depression scale (CES-D)

中文摘要:

      目的 研究老年人群抑郁与冠心病的相关性,为老年冠心病患者的精神卫生健康提供依据.方法 本研究采用流行病学研究用抑郁自评量表(center for epidemiologic studies depression scale,CES-D)评估抑郁情况.将研究对象分为冠心病组与非冠心病组,研究CES-D评分及抑郁症状与冠心病的相关性,并进一步分析CES-D评分及抑郁与糖脂代谢相关生化指标的关系.结果 在3 580例研究对象中,626例(17.5％)存在抑郁.在冠心病组与非冠心病组之间,CES-D评分[9(4～16) vs6(2～12),P＜0.001]及抑郁(26.6％ vs 16.1％,P＜0.001)的差异均具有统计学意义.CES-D评分(OR=1.029,95％CI:1.017～1.042)和抑郁(OR=75.6％,95％CI:1.370～2.250)均为冠心病的独立危险因素.按男女性别亚组进行分析后均仍有统计学差异.抑郁人群与无抑郁人群的血液高密度脂蛋白胆固醇水平存在差异(P＜ 0.05);CES-D评分与糖脂代谢指标不相关.结论 老年人群中CES-D评分得分及抑郁症状与冠心病存在相关性.

英文摘要:

      Objective To explore the correlation between depression and coronary heart disease (CHD) in the elderly population so as to provide basis for psychological health care of the elderly with coronary heart disease.Methods center for epidemiological studies depression scale (CES-D) was applied to the subjects who were divided into 2 groups:CHD group and non-CHD group;the correlation between CES-D scores and CHD was explored and further analysis was made to the relation of CES-D scores and depression with the parameters of glucose and lipid metabolism.Results Depression existed in 626 elderly out of the 3 580 research subjects in total (17.5％);there existed a statistical difference in CES-D scores and depression between CHD group and non-CHD group [9 (4～ 16) vs 6 (2～12),P＜ 0.001] (26.6％ vs 16.1％,P＜0.001);CES-D scores (OR=1.029,95％CI:1.017～1.042) and depression (OR=75.6％,95％CI:1.370～2.250) were the independent risk factors of CHD;analysis between the gender subgroups showed out the same results;the level of high density lipoprotein cholesterol (HDL-C) in patients with depression was statistically different from that of the norm (P ＜ 0.05);CES-D score was irrelative to the parameters of glucose and lipid metabolism.Conclusions There exists a certain correlation among CES-D score,depression symptoms and CHD.