冠状动脉钙化的性别与年龄分布及介入并发症的临床特征

Gender and Age Distribution of Coronary Artery Calcification and Clinical Complications Associated with Percutaneous Coronary Intervention

中文关键词: 冠状动脉  钙化  经皮冠脉介入治疗  流行病学

英文关键词: coronary artery  calcification  percutaneous coronary intervention  epidemiology

中文摘要:

      目的 探讨冠脉造影患者中冠状动脉钙化发生率、性别与年龄分布及现代介入治疗术中并发症的临床特点.方法 回顾分析复旦大学附属中山医院2009年1月-2015年2月接受冠状动脉造影患者,纳入冠状动脉钙化患者,收集冠脉钙化病例数、经皮冠脉介入治疗(PCI)、冠脉旁路手术(CABG)及单纯冠脉造影数、血管内超声(IVUS)检查数、冠脉CTA检查数及介入治疗并发症情况.结果 研究纳入冠脉钙化患者6 742例,占冠脉造影患者的18.2％,其中60 ～ 80岁男性人群为高发人群,占钙化总人群的71.3％;2 872例(42.6％)冠脉钙化患者接受药物或CABG治疗,3 870例(57.4％)患者接受PCI治疗;IVUS指导冠脉钙化病变介入治疗551例,占PCI患者的14.2％,冠状动脉CTA在总钙化患者中的应用比例为6％;钙化病变PCI术支架植入成功率99.5％,最常见手术并发症为冠脉夹层,占比81.2％,无死亡病例.结论 冠脉造影冠脉钙化检出率为18％,老年男性患者为冠脉钙化的高发人群,PCI治疗成功率高且安全,冠脉夹层为常见并发症.

英文摘要:

      Objective To investigate the occurrence of coronary artery calcification,the gender and age distribution and clinical complications of interventional therapy in patients undergoing coronary angiography.Methods A retrospective study was made to cases with coronary calcified lesions verified by coronary angiography during the period from Jan.,2009 to Feb.,2015 in Zhongshan Hospital affiliated to Fudan Univerty,the data on the number of patients with coronary artery calcification,and the number of those undergoing percutaneous coronary intervention (PCI),undergoing coronary artery bypass surgery (CABG),receiving intravascular ultrasound (IVUS) examination,or receiving coronary CTA examination,as well as the number of clinical complications,were collected.Results 6 742 cases with coronary artery calcification were enrolled,taking up 18.2％ of all the cases undergoing coronary angiography;males aged from 60 to 80 years old were high risk population,taking up 71.3 ％ of the cases with coronary artery calcification;2 872 cases (42.6 ％) received drug therapy or CABG,3 870 cases (57.4％) received PCI;IVUS guided interventional therapy were performed in 551 PCI patients (14.2 ％),and coronary CTA examination was performed in 6 ％ of the enrolled patients;the success rate of PCI for coronary calcified lesions was 99.5 ％,and the most common complication was coronary artery dissection (81.2 ％ of all complications);no death occurred.Conclusions The incidence of coronary artery calcification is 18％ in patients undergoing coronary angiography,and male patients aged 60 years old and over were of high risk of coronary artery calcification;PCI is a safe and effective procedure;coronary artery dissection is the most common complication.