文章摘要
潘露露,任玉峰,陈晓燕,贲如琴.老年乳腺癌化疗患者癌因性疲乏现状调查及相关因素分析[J].老年医学与保健,2024,30(3):621-625;632
老年乳腺癌化疗患者癌因性疲乏现状调查及相关因素分析
Investigation and analysis of related factors of cancer-related fatigue in elderly patients with breast cancer undergoing chemo-therapy
  
DOI:10.3969/j.issn.1008-8296.2024.03.011
中文关键词: 老年  乳腺癌  化疗  癌因性疲乏  影响因素
英文关键词: elderly  breast cancer  chemotherapy  cancer-related fatigue  influencing factor
基金项目:MSZ2022023:南通市卫生健康委员会面上课题
作者单位
潘露露 南通市肿瘤医院乳腺外科 
任玉峰 南通市肿瘤医院中西医结合科 
陈晓燕 南通市肿瘤医院乳腺外科 
贲如琴 南通市肿瘤医院中西医结合科 
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中文摘要:
      目的 对老年乳腺癌化疗患者癌因性疲乏(CRF)现状进行调查,并对影响CRF的因素进行分析,为制定相应干预策略提供依据.方法 选取2020年5月—2023年5月在南通市肿瘤医院进行化疗干预的76例老年乳腺癌患者,利用CRF量表对76例老年乳腺癌化疗患者进行CRF评估.比较不同临床特征患者CRF评分差异,利用多元线性回归方法分析影响老年乳腺癌化疗患者CRF的相关因素,并根据相关因素提出干预策略建议.结果 76例老年乳腺癌患者CRF整体水平处于中度疲乏状态,其中轻度疲乏者3例(3.95%)、中度疲乏者45例(59.21%)、重度疲乏者28例(36.84%).老年乳腺癌化疗患者CRF水平在不同年龄、医疗付费方式、家庭月收入、主要照顾者、TNM分期、睡眠状况和化疗前人体质量指数(BMI)差异均具有统计学意义(P<0.05).多元线性回归分析显示,主要照顾者、TNM分期、睡眠状况、化疗前BMI是影响老年乳腺癌化疗患者CRF的独立因素;主要照顾者为伴侣和子女、TNM分期低、睡眠状况良好、化疗前BMI正常的老年乳腺癌化疗患者CRF水平较轻(P<0.05).结论 老年乳腺癌化疗患者普遍存在CRF,多处于中度疲乏状态,建议临床加强患者心理干预、睡眠质量改善、饮食干预等管理.
英文摘要:
      Objective To investigate the current status of cancer-related fatigue(CRF)in elderly patients with breast cancer undergoing chemotherapy,and analyze its influencing factors,so as to provide basis for formulating corresponding inter-vention strategies.Methods A total of 76 elderly patients with breast cancer undergoing chemotherapy in Tumor Hospital of Nantong City between May 2020 and May 2023 were enrolled.Their CRF was evaluated by CRF scale.The differences in CRF scores among patients with different clinical characteristics were compared.The influencing factors of CRF were analyzed by multivariate linear regression analysis.The intervention strategies were proposed according to the related factors.Results The overall level of CRF in 76 elderly patients with breast cancer was moderate fatigue,including 3 ones(3.95%)with mild fa-tigue,45 ones(59.21%)with moderate fatigue,and 28 ones(36.84%)with severe fatigue.The CRF level of elderly breast cancer patients undergoing chemotherapy is different in patients with different ages,medical payment methods,family monthly income,main caregivers,TNM stages,sleep status and body mass index(BMI)before chemotherapy(P<0.05).Multivari-ate linear regression analysis showed that main caregiver,TNM staging,sleep status and BMI before chemotherapy were inde-pendent influencing factors of CRF.CRF was mild in elderly patients with partners and children as the main caregivers,low TNM staging,good sleep status and normal BMI before chemotherapy(P<0.05).Conclusion CRF is common in elderly patients with breast cancer undergoing chemotherapy,and most of them are in a state of moderate fatigue.It is recommended to strengthen the management of patients in clinical practice such as psychological intervention,sleep quality improvement,dietary intervention,etc.
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