SARC-F筛查肌少症效能的优化研究

A study on optimization of SARC-F screening efficacy for sarcopenia

中文关键词: 老年人  肌少症  诊断标准  患病率

英文关键词: elderly  sarcopenia  diagnostic criteria  prevalence

中文摘要:

      目的 探讨SARC-F筛查肌少症效能的优化方法.方法 2018年3月-2021年8月,采用SARC-F评分量表、AWGS2和EWGSOP2诊断共识对受试者进行肌少症诊断,分析诊断一致性,优化SARC-F筛查肌少症的效能.结果 以SARC-F、AWGS2 和 EWGSOP2 诊断的肌少症患病率分别为 12.78％(52/407)、28.26％(115/407)和 31.20％(127/407).以AWGS2和EWGSOP2为金标准,SARC-F≥4分筛查肌少症的灵敏度为37.39％(43/115)和35.43％(45/127),特异度为96.92％(283/292)和97.50％(273/280).受试者操作特征曲线显示,SARC-F的最优诊断截断值为2分.SARC-F≥2 分筛查肌少症的灵敏度为 89.57％(103/115)和 88.98％(113/127),特异度为 76.71％(224/292)和79.29％(222/280).结论 SARC-F≥2分诊断肌少症可能具有更高的灵敏度,更适用于初步筛查.

英文摘要:

      Objective To explore an optimization method of SARC-F screening efficacy for sarcopenia.Methods From March 2018 to August 2021,the SARC-F scoring scale,Asian Working Group for Sarcopenia 2(AWGS2)and European Working Group on Sarcopenia in Older People 2(EWGSOP2)were used to diagnose sarcopenia in the subjects.Results The prevalence of sarcopenia diagnosed by SARC-F,AWGS2 and EWGSOP2 were 12.78％(52/407),28.26％(115/407)and 31.20％(127/407),respectively.Taking AWGS2 and EWGSOP2 as the gold criteria,the sensitivity of SARC-F ≥4 for screening sarcopenia was 37.39％(43/115)and 35.43％(45/127),and the specificity was 96.92％(283/292)and 97.50％(273/280).Receiver operator characteristic curve showed that the optimal cut-off value of SARC-F was 2 points.The sensitiv-ity of SARC-F≥ 2 for screening sarcopenia was 89.57％(103/115)and 88.98％(113/127),and the specificity was 76.71％(224/292)and 79.29％(222/280).Conclusion SARC-F≥2 may have higher sensitivity for diagnosing sarcopenia and is more suitable for initial screening.