半导体激光联合微波治疗在老年带状疱疹的临床观察

Clinical observation of semiconductor laser combined with microwave in treatment of herpes zoster in the elderly

中文关键词: 老年  半导体激光  微波治疗  带状疱疹  带状疱疹后遗神经痛

英文关键词: elderly  semiconductor laser  microwave therapy  herpes zoster  postherpetic neuralgia

中文摘要:

      目的 探讨半导体激光结合微波治疗老年带状疱疹(herpes zoster,HZ)的疗效.方法 选择2022年8月-2024年2月上海市闵行区中心医院皮肤科就诊的120例老年HZ患者,按随机数字表法分为A组、B组和C组,每组40例.A组接受常规的药物治疗.B组接受除常规药物治疗之外,附加半导体激光治疗.C组接受常规药物治疗及半导体激光之外,附加微波治疗.结果 C组(95.0％)的疗效高于A组(67.5％)和B组(82.5％),且组间相比较差异具有统计学意义(P＜0.05).治疗后,视觉模拟评分法(visual analog scale,VAS)评分显示C组(2.63±1.09)分显著低于A组(4.28±1.17)分和B组(3.79±1.03)分,且组间相比较差异有统计学意义(P＜0.05).并且C组的疼痛开始减轻时间(2.13±0.97)d及水疱开始结痂时间(3.46±0.78)d 均早于 A 组(5.21±1.17)d、(6.12±0.07)d和B 组(4.26±1.29)d、(4.95±1.01)d(P＜0.05).观察发现治疗开始后的第2周及第3周,C组的HZ后遗神经痛(postherpetic neuralgia,PHN)总发生率(16％、6％)显著低于A组(31％、23％)和B组(22％、14％)(P＜0.05).结论 半导体激光联合微波治疗老年HZ的疗效显著.

英文摘要:

      Objective To explore the therapeutic effects of semiconductor laser combined with microwave on herpes zos-ter(HZ)in the elderly.Methods 120 elderly HZ patients treated in Department of Dermatology,Central Hospital of Minhang District from August 2022 to February 2024 were selected and divided into group A,group B and group C according to random number table method,with 40 cases in each group.The group A received conventional drug therapy.The group B received semi-conductor laser therapy in addition to conventional drug therapy.The group C received microwave therapy in addition to conven-tional drug and semiconductor laser therapy.Results The therapeutic effect of the group C(95.0％)was higher than those of group A(67.5％)and group B(82.5％),and the difference among the 3 groups was statistically significant(P＜0.05).After treatment,the Visual Analog Scale(VAS)score of the group C(2.63±1.09)was significantly lower than those of group A(4.28±1.17)and group B(3.79±1.03),and the difference among the 3 groups was statistically significant(P＜0.05).The pain relief time(2.13±0.97d)and blister scabbing formation time(3.46±0.78 d)of the group C were earlier than those of the group A(5.21±1.17 d and 6.12±0.07 d)and group B(4.26±1.29 d and 4.95±1.01 d)(P＜0.05).Within 2 and 3 weeks after treatment,the overall incidence of postherpetic neuralgia(PHN)in the group C was significantly lower(16％,6％)than those in the group A(31％,23％)and group B(22％,14％)(P＜0.05).Conclusion The combination of semiconductor laser and microwave therapy has significant therapeutic effects on HZ in elderly patients.