社区老年高血压患者颈动脉病变与血压变异的相关性分析

Correlation analysis of carotid artery lesions and blood pressure variability in elderly hypertensive patients in a community

中文关键词: 社区, 老年高血压患者, 血压变异性, 颈动脉内中膜厚度, 颈动脉病变

英文关键词: community  elderly  hypertensive patient  blood pressure variability  carotid intima-media thickness  carot-id artery lesion

中文摘要:

      目的 分析社区65岁以上老年高血压患者颈动脉疾病与血压变异程度的关系,以期制定社区早期干预策略.方法 选取2022年6月-2023年6月上海市浦东新区某社区460例65岁以上门诊老年患者,依据是否患有高血压病,分为高血压组(HTN组,n=274)和非高血压组(NHTN,n=186),比较2组患者的基本临床资料、实验室指标、颈动脉病变情况,动态血压指标和颈动脉病变的相关性采用pearson相关分析,社区老年高血压患者颈动脉病变的影响因素采用多因素Logistic回归分析.结果 高血压组IMT斑块检出率明显高于非高血压组(x2斑块=28.174,P＜0.05).IMT斑块组和IMT增厚组24 hSBP、dSBP、nSBP、24 hSBPCV、dSBPCV、nSBPCV等动态血压指标均明显高于IMT正常组(P＜0.05).24 hSBP、dSBP、nSBP、24 hSBPCV、nSBPCV是影响颈动脉IMT病变的独立危险因素.结论 老年高血压患者血压变异程度与颈动脉疾病之间具有一定的关联,收缩压血压变异性指标是颈动脉疾病的危险因素,及早干预好这些危险因素可有效预防动脉粥样硬化的发生发展.

英文摘要:

      Objective To analyze the correlation between carotid artery lesions and blood pressure variability in elderly hypertensive patients over 65 years old in the community,and develop early intervention strategies for the community.Methods From June 2022 to June 2023,460 outpatient elderly patients over 65 years old in a community in Pudong New Area,Shanghai were selected.According to whether they had hypertension,they were divided into hypertension group(HTN group,n=274)and non-hypertension group(NHTN group,n=186).The basic clinical data,laboratory indexes and carotid artery le-sions of the two groups were compared.The correlation between dynamic blood pressure indexes and carotid artery lesions was an-alyzed by Pearson correlation analysis.The influencing factors of carotid artery lesions in elderly hypertensive patients in the com-munity were analyzed by multivariate logistic regression analysis.Results The detection rate of carotid intima-media thickness(IMT)plaques in the HTN group was significantly higher than that in the NHTN group(x2plaque=28.174,P＜0.05).The dynam-ic blood pressure indexes,including 24 hSBP,dSBP,nSBP,24 hSBPCV,dSBPCV,and nSBPCV,in the IMT plaque and IMT thickened group were significantly higher than those in the IMT normal group(P＜0.05).24 hSBP,dSBP,nSBP,24 hSBPCV,nSBPCV were independent risk factors for carotid IMT lesions.Conclusion There is a certain association between blood pressure variability and carotid artery lesions in elderly hypertensive patients.Systolic blood pressure variability is a risk factor for carotid artery lesions.Early intervention of these risk factors can effectively prevent the occurrence and development of atherosclerosis.