基于PG-SGA量表观察个体化肠内营养干预对老年溃疡性结肠炎患者的效果影响

Effects of individualized enteral nutrition intervention on elderly patients with ulcerative colitis based on PG-SGA scale

中文关键词: 老年, 溃疡性结肠炎, 肠内营养, 主观整体评估量表, 免疫功能, 营养指标, 生活质量

英文关键词: elderly  ulcerative colitis  enteral nutrition  Subjective Global Assessment Scale  immune function  nutri-tional index  quality of life

中文摘要:

      目的 观察个体化肠内营养干预对老年溃疡性结肠炎患者的PG-SGA量表评分和营养指标影响,以期为临床患者预后改善提供方法.方法 回顾性选择2023年1月-2024年3月在江苏省中医院接受治疗的100例老年活动期UC患者作为研究对象,依据患者不同的营养干预方式分为对照组和观察组.对照组行常规营养管理,观察组在对照组基础上给予个体化肠内营养干预,记录2组干预前后主观整体评估(PG-SGA)量表评分、营养指标、免疫指标和生活质量情况.结果 干预后2组患者PG-SGA量表评分较干预前降低,血清HGB、PA、ALB水平较干预前升高,且观察组PG-SGA量表评分低于对照组,血清HGB、PA、ALB水平高于对照组(P＜0.05).干预后2组患者血清CD8+水平较干预前降低,血清CD4+、CD3+水平较干预前升高,且观察组CD8+水平低于对照组,CD4+、CD3+水平高于对照组(P＜0.05).干预后2组患者SF-36量表各项评分较干预前升高,且观察组又高于对照组(P＜0.05).结论 个体化肠内营养干预可降低老年UC患者PG-SGA量表评分,改善患者免疫功能与营养指标,提高患者生活质量.

英文摘要:

      Objective To observe the effects of individualized enteral nutrition intervention on the score of Subjective Global Assessment(PG-SGA)scale and nutritional indexes in elderly patients with ulcerative colitis(UC),and provide meth-ods for improving the prognosis of clinical patients.Methods 100 elderly patients with active UC treated in Traditional Chi-nese Medicine Hospital of Jiangsu Province from January 2023 to March 2024 were retrospectively selected as the study sub-jects.They were divided into control group and observation group according to different nutritional intervention methods.The control group received routine nutrition management,and the observation group received individualized enteral nutrition inter-vention on the basis of the control group.The PG-SGA scale scores,nutritional indexes,immune indexes and quality of life be-fore and after intervention in the two groups were recorded.Results After intervention,the PG-SGA scores of the two groups were lower than those of the same group before intervention,and the levels of serum HGB,PA and ALB were higher than those of the same group before intervention,and the PG-SGA score of the observation group was lower than that of the control group,and the serum levels of HGB,PA and ALB were higher than those of the control group(P＜0.05).After intervention,the levels of serum CD8+of the two groups was lower than those of the same group before intervention,and the levels of serum CD4+and CD3+were higher than those of the same group before intervention,and the level of CD8+of the observation group was lower than that of the control group,and the levels of CD4+and CD3+were higher than those of the control group(P＜0.05).After intervention,the scores of SF-36 scale of the two groups were higher than those of the same group before inter-vention,and the observation group was higher than the control group(P＜0.05).Conclusion Individualized enteral nutrition intervention can reduce PG-SGA scale score in elderly UC patients,improve their immune function,nutrition indexes and quali-ty of life.