老年慢性阻塞性肺疾病急性期患者一年内再发急性加重情况调查及相关因素分析

Investigation on recurrence of acute exacerbation within one year in elderly patients with COPD during acute phase and analy-sis of its related factors

中文关键词: 老年  慢性阻塞性肺疾病  急性加重  影响因素  肺心病  长期家庭氧疗

英文关键词: elderly  chronic obstructive pulmonary disease  acute exacerbation  influencing factor  pulmonary heart disease  long-term home oxygen therapy

中文摘要:

      目的 调查老年慢性阻塞性肺疾病(COPD)急性期患者1年内再发急性加重情况,并分析相关因素.方法 回顾性选取于2023年1月—2023年12月攀枝花市第二人民医院就诊的384例老年COPD急性期患者的临床资料,根据随访是否再发急性加重,分为再发组(n=161)和未再发组(n=223).采用Logistic回归分析老年COPD急性期患者1年内再发急性加重的危险因素.结果 1年内急性加重再发率为41.93％(161/384).合并肺心病[OR:2.230(1.251～3.976)]、NLR[OR:1.429(1.110～1.840)]、CRP[OR:1.177(1.018～1.361)]是老年 COPD 急性期患者 1 年内再发急性加重的危险因素(P＜0.05),而长期家庭氧疗[OR:0.389(0.189～0.801)]是保护性因素(P＜0.05).结论 老年COPD急性期患者1年内急性加重再发率较高,临床需重点关注合并肺心病以及NLR、CRP高水平的患者,建议患者坚持长期家庭氧疗有助于降低急性加重再发率.

英文摘要:

      Objective To investigate the recurrence of acute exacerbations within one year in elderly patients with chro-nic obstructive pulmonary disease(COPD)during acute phase and analyze its related factors.Methods The clinical data from 384 elderly patients with COPD during acute phase treated in Second People's Hospital of Panzhihua City between January 2023 and December 2023 were retrospectively collected.Based on whether acute exacerbation recurred during follow-up,they were divided into recurrence group(n=161)and non-recurrence group(n=223).Logistic regression analysis was used to identify risk factors for acute exacerbation recurrence within one year in these patients.Results The recurrence rate of acute exacerba-tion within one year was 41.93％(161/384).Concurrent pulmonary heart disease[OR:2.230(1.251-3.976)],elevated NLR[OR:1.429(1.110-1.840)]and elevated CRP[OR:1.177(1.018-1.361)]were risk factors for acute exacerbation recurrence within one year in elderly COPD patients during acute phase(P＜0.05),while long-term home oxygen therapy[OR:0.389(0.189-0.801)]was a protective factor(P＜0.05).Conclusion The recurrence rate of acute exacerbation within one year is high among elderly COPD patients during acute phase.Clinical attention should be focused on patients with concomitant pulmonary heart disease and high levels of NLR and CRP.It is recommended that patients adhere to long-term home oxygen therapy,which is helpful in reducing the recurrence rate of acute exacerbations.