不对称性等速肌力训练联合脑机接口集成功能性电刺激对老年脑卒中患者肢体功能及神经功能的影响

Symmetric isokinetic strength training combined with brain-computer interface integrated functional electrical stimulation on limb function and neurological function in elderly stroke patients

中文关键词: 老年    不对称性等速肌力训练    脑机接口    集成功能性电刺激    卒中    肢体功能

英文关键词: elderly  asymmetric isokinetic strength training  brain-computer interface  integrated functional electrical stimulation  stroke  limb function

中文摘要:

      目的 探索不对称性等速肌力训练联合脑机接口(BCI)集成功能性电刺激(FES)对老年脑卒中患者肢体功能及神经功能的影响。方法 选取2022年3月至2024年3月首都医科大学附属北京康复医院收治的老年脑卒中患者100例，按患者意愿分为单一训练组(n=50)和联合训练组(n=50)。单一训练组接受不对称性等速肌力训练，联合训练组接受不对称性等速肌力训练联合BCI-FES。分别于干预前、干预2周后、干预4周后比较2组肢体功能及日常生活活动能力、神经功能、脑电相关指标、表面肌电信号以及不良反应发生率。结果 干预2、4周后，联合训练组Fugl-Meyer运动功能量表评分、改良Barthel指数、运动关联皮层电位、α/β波比值、积分肌电值、均方根振幅大于单一训练组(P<0.05),Wolf运动功能测试时间、美国国立卫生研究院卒中量表评分、改良Rankin量表评分小于单一训练组(P<0.05)。2组不良反应发生率差异无统计学意义(P>0.05)。结论 不对称性等速肌力训练联合BCI-FES方案能一定程度增强肢体功能及日常生活活动能力，改善神经功能和脑电相关指标。

英文摘要:

      Objective To explore the effects of asymmetric isokinetic strength training combined with brain-computer interface(BCI)integrated functional electrical stimulation(FES)on limb function and neurological function in elderly stroke patients.Methods A total of 100 elderly stroke patients admitted to Beijing Rehabilitation Hospital from March 2022 to March 2024 were selected and divided into single training group(n=50)and combined training group(n=50)according to patients′wishes.The single training group received asymmetric isokinetic strength training,while the combined training group received asymmetric isokinetic strength training combined with BCI-FES.Limb function,activities of daily living,neurological function,electroencephalogram-related indicators,surface electromyography signals,and incidence of adverse reactions were compared between the two groups before intervention,after 2 weeks of intervention,and after 4 weeks of intervention.Results After 2 and 4 weeks of intervention,the Fugl-Meyer assessment scale score,modified Barthel index,movement-related cortical potentials,α/β wave ratio,integrated electromyography value,and root mean square amplitude in the combined training group were greater than those in the single training group(P<0.05),while the Wolf motor function test time,national institutes of health stroke scale score,and modified Rankin scale score were lower than those in the single training group(P<0.05).There was no statistically significant difference in adverse reactions between the two groups(P>0.05).Conclusion The combination of asymmetric isokinetic strength training and BCI-FES can enhance limb function and activities of daily living,and improve neurological function and electroencephalogram-related indicators to a certain extent.